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Intra Cytoplasmic Sperm Injection (ICSI) is a relatively new procedure preformed if there is a question of the sperm's ability to fertilize the egg. This can be accomplished even if there is a low sperm count or if there is poor sperm quality. The ICSI procedure is performed similar to regular IVF but with ICSI, the eggs and sperm are retrieved and then inseminated within the laboratory by direct injection of a single sperm into each egg. Three to five days later the resulting embryos are simply placed into the uterus with no surgery, just as with IVF.

The availability of this Intra-Cytoplasmic Sperm Injection, "ICSI" technique means that men whose sperm previously were too weak or too few to fertilize by conventional in vitro fertilization (IVF), now should have little problem in most cases in fertilizing their wife's eggs. The fertilization rate per egg using ICSI is about 70%, the fertilization rate per infertile couple is over 99% if the wife has adequate eggs. This rate is very similar to IVF with normal sperm.
For more information on the IVF process, please read from some of these sources:

American Society for Reproductive Medicine

Resolve: The National Infertility Association




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